Zoladex Injection Components
Zoladex injection contains Goserelin, a synthetic analog to the luteinizing hormone-releasing hormone (LHRH) secreted by the body naturally, and with the use of the drug and increased levels of that hormone, testosterone levels in men and estrogen in women decrease, helping to treat prostate cancer and breast cancer.
Zoladex uses
Zoladex is used to treat:
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Hormone-responsive prostate cancer.
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Adjuvant treatment for prostate cancer along with radiotherapy.
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Receptor-positive breast cancer before menopause.
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Relieve the symptoms of endometriosis, and reduce the number of endometrial lesions.
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Treat fibroids by reducing their size and relieving their symptoms.
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Reduce the thickness of the endometrium before ablation of the endometrium.
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Assisted reproduction.
Zoladex Dosage
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The appropriate dose is determined by the doctor.
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The usual dose is one injection of 3.6 mg Zoladex every 28 days injected under the skin into the anterior abdominal wall.
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Care should be taken when injecting Zoladex into the anterior abdominal wall due to proximity to the inferior epigastric artery and its branches.
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If Zoladex is used to treat gynecological diseases, it should be used only for 6 months for possible osteoporosis.
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Once used as an adjuvant treatment with radiotherapy, the use of antiestrogen may be required for a short time to prevent flare.
Zoladex side effects
Zoladex injections may cause some side effects, such as:
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Hot flushes.
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excessive sweating.
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Decreased libido.
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Pain in the injection site.
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Heart failure.
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Rash.
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Gynecomastia.
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Bone pain.
Zoladex contraindications
Zoladex is not used with:
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Allergy to drug ingredients.
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Pregnancy and lactation.
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Not used for children.
Zoladex Use Precautions
The doctor should be consulted before using Zoladex injections, especially in the case of:
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Ureteric obstruction or renal impairment.
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Spinal cord compression
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Diabetes.
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Heart disease, especially heart attack.
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osteoporosis.
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PCOS, especially with the use of the drug in assisting reproduction.
