Sprycel 50 mg 60 Tablets is a medication used to treat leukaemia (blood cancer) in adults and children, especially in patients who have shown resistance or intolerance to previous treatments.

Sprycel Composition

Sprycel contains the active ingredient dasatinib, which works by inhibiting specific proteins inside leukaemia cells that are responsible for their excessive growth. This helps kill the leukaemia cells in the bone marrow and allows the production of normal blood cells.

Sprycel uses

For adults:

• Newly diagnosed Philadelphia chromosome-positive chronic myeloid leukaemia (Ph+ CML) in chronic phase.

• Chronic, accelerated, or blast-phase CML resistant or intolerant to prior therapy, including imatinib.
  
  

• Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph+ ALL) or lymphoid blast-phase CML resistant or intolerant to prior therapy.

For children:

• Ph+ CML in chronic phase, either newly diagnosed or resistant/intolerant to previous therapy, including imatinib.

• Newly diagnosed Ph+ ALL, administered in combination with chemotherapy.

Sprycel 50 mg Dosage

• Adults: The usual starting dose is 100 mg once daily.
  The doctor may adjust the dose based on the patient’s condition.

• Children: The doctor determines the appropriate dose according to weight and medical condition.

• Avoid grapefruit or grapefruit juice while taking this medicine.

Sprycel Side Effects

Sprycel may cause some side effects, such as:

• Headache

• Dizziness

• Tingling or numbness in the limbs

• Diarrhoea

• Nausea or vomiting

• Fever or infections

• Shortness of breath, cough

• Abdominal pain

• High blood pressure

• Hair loss

• Blurred vision

• Weight loss

Contraindications

Do not use Sprycel if you have:

• Hypersensitivity to any of its components

• Pregnancy or are planning to become pregnant

Warnings and Precautions

Tell your doctor before taking Sprycel if you have any of the following conditions:

• Kidney disease

• Liver disease

• Heart problems

• Lactose intolerance

• Hepatitis B infection

• Breastfeeding

Drug Interactions

Inform your doctor about any other medications you are taking, as some may interact with Sprycel, including:

• Antifungal drugs (e.g., ketoconazole)

• Dexamethasone

• Antiepileptic drugs

• Anticoagulants (blood thinners)

• Diabetes medications

• Antibiotics

• Antiviral medications

Storage Instructions

• Keep out of reach of children.

• Store at a temperature not exceeding 30°C.

• Do not use the medicine after the expiry date printed on the package.