Mounjaro Pen 2.5 mg helps with excessive weight loss and regulates blood sugar levels by slowing digestion and reducing appetite, supporting weight loss. It is used only once a week.
Time frame |
Mounjaro dose |
Weight loss |
First Week |
2.5 mg |
Rapid weight loss or slow progression |
Second Week |
2.5 mg |
1% of weight |
Third and fourth Weeks |
2.5 mg |
up to 4% of weight |
5th to 8th week |
5 mg |
5 - 6% of weight |
9th to 12th week |
7.5 mg |
9 - 12% of weight |
13th week |
10 mg |
13% of weight |
onwards |
12.5 mg in the 17th week. 15 mg in week 21 and after. |
About 21% of beginning weight after a year of using the drug. |
The active ingredient in Mounjaro mimics GLP-1 and GIP hormones, which are secreted by the digestive system after eating to regulate blood sugar levels. These hormones signal the body to produce more insulin and slow digestion, helping reduce blood sugar levels and support weight loss.
Mounjaro Pen 2.5 mg is used for:
Treating type 2 diabetes
Weight loss
Mounjaro injections are administered subcutaneously once a week.
They can be injected into the abdomen, thigh, or upper arm.
The injection site should be rotated each time.
It can be taken at any time of the day, with or without meals.
The doctor may increase the dose after 4 weeks.
The maximum dose allowed is 15 mg once weekly.
If less than 4 days have passed, take the missed dose.
If more than 4 days have passed, skip the missed dose and take the next one on schedule.
The weekly injection day can be adjusted if at least 3 days have passed between doses.
Mounjaro begins working within hours after the first injection and takes 8 - 72 hours to reach peak levels in the blood.
A 2022 study published in The New England Journal of Medicine found that people who used tirzepatide (Mounjaro’s active ingredient) for 72 weeks:
Lost 19.5% of their body weight on a 10 mg dose
Lost 20.9% of their body weight on a 15 mg dose
Side effects |
Tips to reduce them |
Nausea (12 - 18%) |
- Eat small meals throughout the day. - Avoid fatty foods. - Drinking appropriate quantities of water. - Do not lie down after eating. - Eating mint or ginger. |
Diarrhea (12 - 17%) |
-Drink appropriate quantities of water constantly. - Avoid spicy and greasy foods. - Eat smaller meals. - Taking anti-diarrhoea drugs after consulting a doctor. |
Decreased appetite (5 - 11%) |
-Eat foods rich in nutrients, such as fruits, vegetables and whole grains. - Regular exercise to stimulate appetite. - Improve the flavors of food. - Eat smaller meals throughout the day. |
Dyspepsia (5 - 8%) |
- Chewing food slowly. - Wear wide and comfortable clothing. - Eat smaller meals. - Do not lie down immediately after eating. - Reduce caffeine and alcohol intake. |
Constipation (6 - 7%) |
- Eat high-fibre foods, such as whole grains or vegetables and fruits. - Regular exercise. - Drinking appropriate quantities of water. - Go to the toilet regularly. |
Stomach pain (5 - 6%) |
-Avoid spicy foods. - Steam meat and vegetables instead of frying them in butter or oil. - Eat smaller meals throughout the day. |
Mounjaro may also cause injection site pain or an increased heart rate.
Side effects usually disappear within days or weeks after starting Mounjaro.
Consult a doctor if Mounjaro side effects persist or worsen. Some individuals may be at higher risk of severe side effects:
Inform your doctor if you or a family member has had thyroid cancer, as Mounjaro may increase the risk. Seek medical advice if you experience a neck lump, trouble swallowing or breathing, or hoarseness.
Some Monjuaro users may develop pancreatitis, so you should stop Mounjaro and consult a doctor if you experience severe abdominal pain, back pain, or vomiting.
Combining Mounjaro with other diabetes drugs can cause low blood sugar, so you should consult your doctor, especially if you are taking insulin or other diabetes medications.
Mounjaro is not recommended for severe stomach problems, such as gastroparesis, as it may worsen digestive symptoms.
People with kidney disease should use Mounjaro cautiously. Side effects like vomiting or diarrhea may cause dehydration, worsening kidney problems, so you should drink enough water, especially if you have kidney disease.
Mounjaro may worsen diabetic retinopathy. Consult a doctor for dose adjustments and have regular eye checkups.
Though rare, some Mounjaro users may develop gallbladder problems, such as gallstones. Seek medical help if you experience upper right abdominal pain, nausea, vomiting, or fever.
Avoid Mounjaro if you have allergies to its ingredients. Severe allergic reactions may include rash, swelling of the face or tongue, or difficulty breathing.
Consult a doctor before using Mounjaro injections during pregnancy or breastfeeding, as it is unknown whether the medication passes to the fetus or infant.
Mounjaro injections should not be used in individuals with:
Severe allergic reactions to its ingredients
A history of medullary thyroid cancer or multiple endocrine neoplasia type 2 (MEN2)
Pros |
Cons |
Taken once weekly |
Injections only |
Can reduce HbA1c by up to 2.4% |
May cause some side effects, such as nausea and stomach pain |
Can be taken with or without meals |
Not recommended for children |
Ready to use pens with needles attached to it |
Not safe for pregnant |
Keep out of reach of children.
Store in the refrigerator at a temperature between 2°C and 8°C.
It can be kept at room temperature (30°C) for up to 21 days only.
Store in its original packaging, away from light.
Mounjaro may help with a weight loss of 15% - 26.6% over 72 - 84 weeks of use. It enhances the feeling of satiety and helps regulate blood sugar levels.
Weight loss varies from person to person. However, according to clinical trials, with a gradual increase in the Mounjaro dose from 2.5 mg in the first week to 15 mg by the 21st week, the expected weight loss is:
4% of body weight in the first month.
9% - 12% of body weight by the end of the third month (on a 7.5 mg dose).
21% of body weight after 12 months (on a 15 mg dose).
Weight loss generally depends on other factors, such as diet, exercise, and adherence to treatment.
Mounjaro injections can be taken before or after meals.
No, Mounjaro is only available as an injection.
Both Mounjaro and Ozempic help with weight loss, but Mounjaro is considered more effective. Clinical trials showed that:
Mounjaro led to a 26.6% weight loss over 84 weeks.
Ozempic resulted in only a 15% weight loss over the same period.
Additionally, both Mounjaro and Ozempic help lower HbA1c (glycated hemoglobin) levels, which may take 2 - 3 months to reach the desired levels.
Mounjaro |
Ozempic |
|
Weight loss |
More efficient |
Less efficient |
HbA1c |
More efficient |
Less efficient |
Active ingredient |
Tirezepatide (work on GLP-1 and GIP receptors) |
Semaglutide (Works on GLP-1 only and doesn’t work on GIP receptors) |
Method of use |
Subcutaneous injection once weekly |
Subcutaneous injection once weekly |
Side effects |
more |
less |
Dose |
2.5 - 15 mg |
0.5 - 2 mg |
Obesity is a risk factor for cancer. Mounjaro, when used alongside a healthy diet and regular exercise, may help with weight loss and potentially reduce the risk of cancer.
Mounjaro may cause diarrhea in some people. It is recommended to drink adequate amounts of water if this occurs and consult a doctor if the diarrhea persists for a long time or worsens.
Some people have reported experiencing headaches while using Mounjaro injections. However, Mounjaro may not directly cause headaches; instead, they could result from low blood sugar levels or dehydration due to the medication’s effects.
A small percentage of Mounjaro users have reported experiencing depression, anxiety, or mood changes.
Yes, Mounjaro injections may affect the menstrual cycle, especially in women who are overweight and have irregular periods. Weight loss may help regulate the cycle.
Rapid weight loss may lead to temporary hair loss. Some people using Mounjaro may experience hair shedding, especially due to weight loss. However, this is usually temporary, and hair growth resumes once the body adapts to the changes, though it may take some time.
Each Mounjaro pen contains 4 doses.
One Mounjaro pen contains 2.4 mL.
Mounjaro is administered as a subcutaneous injection in one of the following areas:
The abdomen, at least 5 cm away from the navel.
The thigh.
The upper arm.
It is recommended to rotate the injection site each week.
Mounjaro is available in several doses:
- 2.5 mg
- 5 mg
- 7.5 mg
- 10 mg
- 12.5 mg
- 15 mg