CO APROVEL 150 / 12.5 MG 28 TABLETS

Co aprovel 150/12.5 mg tab

scientific name

Irbesartan 150mg + Hydrochlorothiazide 12.5mg Tablets

Category of Co-Aprovel 150/12.5 Tablets

Antihypertensive drugs

Mechanism of action of co aprovel 150/12.5 mg

Irbesartan is an angiotensin II receptor blocker (ARB). It works by blocking substances in the body that cause blood vessels to narrow.

This causes irbesartan to relax blood vessels. This lowers blood pressure and increases blood and oxygen flow to the heart.

Hydrochlorothiazide inhibits sodium chloride transport in the distal convoluted tubule. More sodium is then excreted with fluid in the kidneys.

As a result, it increases urine output, which in turn decreases blood volume and ultimately blood pressure.

When used chronically, thiazide diuretics (TZDs)-mediated reductions in chronic arterial pressure are thought to occur through reductions in peripheral vascular resistance.

Therapeutic Indications for Co-Aprovel 150/12.5 Tablets

Treat essential hypertension.

This fixed-dose combination is indicated for adult patients whose blood pressure is not adequately controlled with irbesartan or hydrochlorothiazide alone

High blood pressure is a common condition in which the chronic pressure of blood on the walls of arteries is high enough that it can eventually lead to health problems such as heart disease.

Administration of Co-Aprovel 150/12.5 Tablets

1. Tablets may be taken with or without food.

2. Swallow the tablets with enough water (such as a glass).

3. If possible, take your daily dose at the same time each day, such as with breakfast.

4. Always take this medicine exactly as your doctor tells you to. If you are unsure, ask your doctor or pharmacist.

5. The recommended starting dose is one tablet once daily. However, if your blood pressure is not under control, your doctor may decide to change your dose

6. Doses exceeding 300 mg irbesartan/25 mg hydrochlorothiazide once daily are not recommended.

7. The dosage may be altered in special cases, so always follow the advice of your doctor or pharmacist.

8. If you take more than you should, consult your doctor or go to a hospital right away.

9. If you forget to take your medicine, take it as soon as you remember, unless it is almost time for your next dose.

10. Do not take a double dose (two doses at a time) to make up for a missed dose.

Co-Aprovel 150/12.5 Tablet Adverse Side Effects

• Dizziness

• Elevated blood urea nitrogen (BUN), creatinine, and creatine kinase

• postural vertigo

• Headache

• cough

• feel sick and vomit

• hyperkalemia

• Pregnancy and breastfeeding precautions while taking Co-Aprovel 150/12.5 Tablets

  • If you are pregnant or breastfeeding, think you may be pregnant or planning a baby, consult your doctor or pharmacist before taking this medicine.

For More Information About co aprovel 150/12.5

- Consult your doctor or pharmacist

-By communicating with the pharmacist of Al-Jawaher Pharmacy on What’s app 0563649160