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Methotrexate is an anti-metabolite that interferes with the growth of some cells of the body, especially cells that multiply rapidly, such as: cancer cells, bone marrow cells, and skin cells.
Dosage:
Treatment of psoriasis and rheumatoid arthritis: One dose per week or three doses taken 12 hours apart once per week.
Cancer treatment: The frequency of doses varies according to the type of cancer and the stage of disease progression.