Zoron 8 Mg Tablets are oral tablets containing 8 mg of the active ingredient Ondansetron, which belongs to the class of 5-HT3 serotonin receptor antagonists. It is used to control nausea and vomiting caused by certain medical procedures.

Indications for Use

Zuron 8 mg is used for the prevention and treatment of nausea and vomiting associated with:

• Chemotherapy (in adults and children).

• Radiotherapy (in adults only).

• Surgical procedures (in adults only).

It should only be used with a medical prescription and is not recommended for other purposes without consulting a doctor.

How to Use Zuron Tablets

• Take Zuron exactly as prescribed by your doctor. Do not hesitate to ask your doctor or pharmacist if you're unsure about the correct method of use.

• Dosage depends on the medical condition and treatment plan determined by your doctor.

For prevention of nausea and vomiting due to chemotherapy or radiotherapy

• Adults:

• On the day of treatment: 8 mg one to two hours before the session, followed by another 8 mg dose after 12 hours.

• On the following days: 8 mg twice daily, for up to 5 days.

• Children over 6 months and adolescents:

• The doctor will determine the dosage based on body weight or surface area.

• A common dose is up to 4 mg twice daily, for up to 5 days.

For prevention of postoperative nausea and vomiting

• Adults: 16 mg before surgery.

• In moderate to severe liver impairment:

• The total daily dose should not exceed 8 mg.

Important Notes:

• Zuron usually starts to work within 1–2 hours of taking the tablet.

• If you vomit within an hour of taking a dose, you may repeat the same dose.

• Do not take an extra dose without consulting your doctor.

• In case of overdose, seek medical attention immediately and take the medicine pack with you.

Administration Instructions:

• Swallow the tablet whole with a glass of water.

• Do not chew or crush the tablet.

• Do not stop the medication or adjust the dose without your doctor's advice.

Side Effects of Zuron Tablets

Common side effects are usually mild and may include:

• Headache.

• Flushing or a warm sensation.

• Mild stomach cramps.

• Constipation or diarrhea.

• Dry mouth.

• Hiccups.

There is generally no need to stop the medication unless the side effects are bothersome or prolonged.

Precautions and Warnings

Do not take this medication if you:

• Are allergic to Ondansetron or any of its ingredients.

• Are taking Apomorphine.

• Are pregnant or breastfeeding without medical approval.

• Have expired medication or damaged packaging.

Inform your doctor if you:

• Have liver problems.

• Are pregnant, planning to become pregnant, or breastfeeding.

• Have a history of allergies to drugs, food, or preservatives.

• Currently have or previously had heart problems.

Drug Interactions

• Zuron should not be used with Apomorphine (used for Parkinson’s disease) due to the risk of serious reactions.

Tell your doctor if you are taking:

• Antiepileptics: such as Carbamazepine or Phenytoin.

• Rifampicin: used to treat infections like tuberculosis.

• Certain antibiotics: such as Erythromycin or Ketoconazole.

• Antiarrhythmic medications: for heart rhythm disorders.

• Beta-blockers: used for heart or eye conditions, anxiety, or migraine prevention.

• Tramadol: a strong pain reliever.

• Heart-affecting drugs: like Haloperidol or Methadone.

• Cancer medications: especially Anthracyclines and Trastuzumab.

• Selective Serotonin Reuptake Inhibitors (SSRIs): such as Fluoxetine, Paroxetine, Sertraline, Fluvoxamine, Citalopram, and Escitalopram (used for depression and anxiety).

• Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs): such as Venlafaxine and Duloxetine.

Storage Instructions

• Keep the medication in its original packaging until use.

• Store in a cool, dry place below 30°C.

• Keep away from direct sunlight and moisture.

• Keep out of reach of children.

Ingredients

Active ingredient:

• Ondansetron 8 mg.

Other ingredients (core):

• Lactose monohydrate.

• Pregelatinized starch.

• Microcrystalline cellulose.

• Sodium starch glycolate.

• Colloidal silicon dioxide.

• Magnesium stearate.

Coating ingredients:

• Opadry Yellow (contains hypromellose, talc, macrogol, titanium dioxide, and yellow iron oxide).