Xigduo Xr 5/500 Mg 28 Tablet is a medication that contains two active ingredients: Dapagliflozin (5 mg) and Metformin Hydrochloride (500 mg) in an extended-release tablet form. It is used to treat type 2 diabetes in adults, especially when blood sugar levels are not adequately controlled with metformin alone.

Benefits and Uses

• Xigduo XR is used to improve blood sugar control in adults and children (from 10 years of age) with type 2 diabetes. It should be taken alongside a healthy diet and regular exercise.

• It contains a combination of dapagliflozin and metformin:

• Dapagliflozin helps the kidneys remove excess sugar from the blood.

• Metformin reduces glucose production in the liver and limits its absorption in the intestines.

• Xigduo XR reduces the risk of hospitalization due to heart failure in adults with type 2 diabetes and heart disease, as well as those with chronic kidney disease.

• It also helps lower the risk of kidney disease complications and death due to heart disease.

• It is not used to treat type 1 diabetes.

How to Use Xigduo Xr 5/500 Mg

• Recommended dose: One tablet daily in the morning with food to reduce stomach upset.

• Swallow the tablet whole without crushing or breaking it.

• Follow your doctor’s instructions carefully and do not change the dose without consulting them.

Side Effects of Xigduo Xr 28 Tablet

• Genital yeast infections.

• Headache.

• Nausea, vomiting, diarrhea.

• Nasal congestion or runny nose, sore throat.

• Kidney or bladder infections.

Contraindications

Do not use this medication in the following cases:

• Severe kidney impairment or dialysis.

• Diabetic ketoacidosis or metabolic acidosis.

• Known allergy to any of the drug's components.

• Temporary discontinuation is required before radiologic imaging that involves contrast dye.

Precautions and Warnings

• In rare cases, serious genital infections may occur. Contact your doctor immediately if you experience:

• Itching.

• Unusual discharge.

• Pain or swelling in the genital area.

• Tell your doctor before using the medication if you have a history of:

• Liver or kidney disease.

• Frequent or severe infections.

• Low blood pressure.

• Heart or bladder problems.

• Previous pancreatic surgery.

• Low-sodium diet.

• Use of medications like insulin or diuretics.

• Infections of the penis or vagina.

• Pregnancy or breastfeeding.

• It may cause lactic acidosis, a serious condition requiring immediate medical care. Symptoms may include:

• Unusual muscle pain.

• Difficulty breathing.

• Dizziness.

• Feeling extremely cold.

Drug Interactions

Tell your doctor if you are using any of the following:

• Digoxin.

• Rifampin.

• Phenytoin.

• Diuretics.

• Other diabetes medications.

• NSAIDs (e.g., aspirin, ibuprofen, naproxen).

Storage

• Store at room temperature, away from moisture and heat.

• Keep out of reach of children.

Ingredients of Xigduo 5/500 Mg 28 Tablet

• Active Ingredients:

• Dapagliflozin.

• Metformin Hydrochloride.

• Other Ingredients:

• Lactose.

• Cellulose.

• Magnesium stearate.

• Silicon dioxide.

• Coating:

• Polyethylene glycol.

• Titanium dioxide.

• Coloring agents.