Xigduo Xr 10/500 - 28 Tablets

Xigduo XR 10/500 mg is a medication used to help control blood sugar levels in adults with type 2 diabetes. It contains two active ingredients: dapagliflozin 10 mg and metformin hydrochloride extended-release 500 mg. The medication works in conjunction with a healthy diet and physical activity to improve glycemic control and may help reduce the risk of certain complications in appropriate patients, as evaluated by a physician.

What is XIGDUO XR 10 500mg used for?

• Improves blood sugar control in adults with type 2 diabetes.

• Improves the body's response to insulin.

• Decreases glucose production in the liver.

• Increases the elimination of excess glucose through urine.

• May help reduce the risk of hospitalization for heart failure and slow the progression of chronic kidney disease in select patients, as determined by a doctor.

Note: This medication is not used to treat type 1 diabetes or diabetic ketoacidosis.

When is the best time to take XIGDUO XR?

• Use exactly as directed by your doctor.

• Take usually once daily with food to help reduce stomach upset.

• Swallow the tablet whole; do not crush, chew, or divide it, as it is an extended-release formulation.

• Strictly adhere to the recommended diet and physical activity plan during treatment.

• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose.

What is the side effects of XIGDUO XR?

Xigduo XR may cause some side effects, the most common being:

• Nausea or diarrhea

• Stomach upset or pain

• Headache

• Increased urination

• Urinary tract infections (UTIs)

• Genital yeast infections

• Dizziness or feeling thirsty

Seek immediate medical attention if you experience symptoms that may indicate serious complications, such as:

• Lactic Acidosis: Severe fatigue, difficulty breathing, unexplained muscle pain, or unusual sleepiness.

• Diabetic Ketoacidosis: Nausea or vomiting, abdominal pain, rapid breathing, or confusion.

Precautions and Warnings

• Do not use for type 1 diabetes or diabetic ketoacidosis.

• Use with caution in patients with kidney or liver disease; regular monitoring of kidney function is required.

• May increase the risk of dehydration, especially in the elderly or patients taking diuretics (water pills).

• Inform your doctor of all medical conditions and medications before starting treatment.

• You may need to temporarily stop this medication before certain imaging procedures involving iodine-based contrast agents, or before certain surgeries, according to your doctor's instructions.

• Maintain adequate fluid intake during treatment, unless advised otherwise by your doctor.

Drug Interactions

Xigduo XR may interact with certain medications, including:

• Insulin and other diabetes medications, which may increase the risk of hypoglycemia (low blood sugar).

• Diuretics (water pills), as they can increase the risk of dehydration and low blood pressure.

• Certain blood pressure medications.

• Drugs that may affect kidney function.

• Iodine-containing contrast agents used in some X-ray scans.

Always inform your doctor or pharmacist of all medications, dietary supplements, and herbal products you are taking before starting treatment.

Storage

• Store at room temperature.

• Keep away from moisture and direct heat.

• Store in the original, tightly closed container.

• Keep out of reach of children.

• Do not use after the expiration date printed on the package.

Ingredients

Active Ingredients (per tablet):

• Dapagliflozin: 10 mg

• Metformin Hydrochloride Extended-Release: 500 mg

Inactive Ingredients:

• Microcrystalline Cellulose

• Hypromellose

• Magnesium Stearate

• Polyethylene Glycol

• Titanium Dioxide

• Iron oxides and other pharmaceutical coating materials