Sodium Chloride 3% Injection - 10ml Ampoule

What is 3% Sodium Chloride Injection?

3% Sodium Chloride Injection is a sterile hypertonic saline solution containing a higher concentration of sodium chloride than isotonic 0.9% saline. It is administered intravenously in specific medical situations requiring sodium and chloride replacement or an increase in blood sodium levels, based on the physician’s assessment and the patient’s clinical condition.

Each 1 mL contains 30 mg of sodium chloride, while a 10 mL ampoule contains a total of 300 mg of sodium chloride. Due to its high concentration and hypertonic nature, it should be used under medical supervision with appropriate monitoring of sodium levels and fluid balance.

Benefits and Uses of 3% Sodium Chloride Solution

• Provides a concentrated source of sodium and chloride when medically indicated.

• May be used as part of treatment protocols for hyponatremia when hypertonic saline is indicated.

• Helps increase blood sodium levels when administered at the dose and rate determined by the physician.

• Contains a higher sodium concentration than 0.9% sodium chloride solution, making it suitable for specific medical conditions requiring a hypertonic solution.

• Comes in a sterile 10 mL ampoule intended for medical use.

Directions for Use

• For intravenous administration only by a physician or qualified healthcare professional.

• The physician determines the dose and rate of administration based on the patient’s age, weight, clinical condition, blood sodium level, and treatment objectives.

• Hypertonic saline should be administered at an appropriate rate with monitoring of sodium levels, electrolytes, and fluid balance to reduce the risk of complications.

• Do not use the ampoule or determine the dose or infusion rate without medical supervision.

• Follow the physician’s instructions and the product leaflet regarding the method of administration and compatibility with other solutions or medications.

Precautions and Warnings

• Use under medical supervision only.

• Sodium and electrolyte levels should be monitored during treatment according to the patient’s condition.

• Use with caution in patients with heart failure, renal impairment, or those at risk of fluid retention.

• Administration at an excessive rate or in an excessive amount may cause hypernatremia or fluid overload.

• Rapid or excessive correction of hyponatremia should be avoided, as rapid changes in sodium levels may cause serious neurological complications.

• Excessive administration may result in fluid retention or edema, including pulmonary edema in susceptible patients.

• Inspect the solution before use. Do not use if it is cloudy, contains particles, or if the container is damaged.

• Use only according to the dose and method of administration specified by the physician or in the product leaflet.

Possible Side Effects and Complications

Some side effects or complications may occur, particularly when the solution is administered at an inappropriate dose or rate, including:

• Increased blood sodium levels (hypernatremia).

• Electrolyte disturbances.

• Fluid overload and edema.

• Increased blood pressure in some patients.

• Shortness of breath or pulmonary edema due to fluid overload in severe cases.

• Pain, irritation, or inflammation at the injection or infusion site.

Serious neurological complications may occur following overly rapid correction of hyponatremia. Therefore, treatment and monitoring should be carried out by a qualified healthcare team.

Storage

• Store below 25°C, away from heat and direct sunlight.

• Keep out of the reach of children.

• Do not use if the container is damaged, or if the appearance of the solution has changed or particles or sediment are present.

• The ampoule is intended for single use only. Discard any unused solution according to appropriate medical procedures.

Ingredients of 3% Sodium Chloride Solution

Active ingredient:

• Sodium chloride 3%.

• Each 1 mL contains 30 mg of sodium chloride.

• Each 10 mL ampoule contains 300 mg of sodium chloride.

Inactive ingredient:

• Water for Injection.

Frequently Asked Questions

What is the difference between 3% and 0.9% sodium chloride solution?

Both solutions contain sodium chloride, but 3% sodium chloride is more concentrated and is considered a hypertonic solution. Therefore, it is used for specific medical conditions under medical supervision, whereas 0.9% sodium chloride has a broader range of medical uses.

Can 3% sodium chloride be used at home?

No. It is a hypertonic intravenous solution that must be administered by a physician or qualified healthcare team with appropriate monitoring. It should not be self-administered at home.

Does 3% sodium chloride treat hyponatremia?

It may be used as part of the treatment of certain cases of hyponatremia. However, the choice of solution, dose, and rate of administration depends on the severity of hyponatremia and the patient’s clinical condition and must be determined by a physician.

How much sodium chloride is in a 10 mL ampoule?

A 10 mL ampoule of 3% sodium chloride solution contains 300 mg of sodium chloride, equivalent to 30 mg per 1 mL.