Sodium Bicarbonate 8.4% Injection - 50ml

Sodium Bicarbonate 8.4% Injection 50 ml is a sterile solution for intravenous injection containing Sodium Bicarbonate at a concentration of 8.4%, equivalent to 84 mg or 1 mEq per ml. It acts as a systemic alkalizer for acidosis and a source of sodium and bicarbonate ions. It is used in hospitals to treat certain cases of metabolic acidosis and conditions requiring alkalinization of the blood or urine, based on physician assessment and laboratory results.

What is a sodium bicarbonate injection used for?

• Helps correct metabolic acidosis in appropriate cases.

• Elevates blood bicarbonate levels and helps increase blood pH.

• Acts as a systemic alkalizer for acidosis.

• Provides sodium and bicarbonate ions to replenish specific deficiencies.

• Can be used in certain cases of drug toxicity requiring urinary alkalinization, according to physician evaluation.

• Used in specific emergency situations, such as certain cardiac arrest cases accompanied by acidosis, per medical protocols and clinical status.

How to Use

• Administered via intravenous injection only by a physician or trained medical healthcare provider.

• Dosage and rate of administration vary depending on the patient's age, weight, severity of acidosis, blood gas analysis, electrolyte levels, and clinical condition.

• The product, dose, or infusion rate must not be self-determined; administering sodium bicarbonate in inappropriate amounts or speeds may cause severe sodium, fluid, or acid-base balance disorders.

Precautions and Warnings

• Use under strict medical supervision within an appropriate healthcare setting.

• Exercise caution in patients with heart failure, severe renal impairment, or conditions associated with sodium retention and edema.

• Administration may lead to hypernatremia or fluid overload, particularly in patients with impaired renal function.

• Serum sodium, potassium, bicarbonate levels, fluid balance, and blood gases must be monitored during use, as clinically indicated.

• Excessive administration may result in metabolic alkalosis.

• Avoid rapid administration or large volume infusion without proper monitoring.

• Contraindicated in certain cases of chloride loss accompanied by vomiting or continuous gastric suction, as well as conditions causing hypochloremic metabolic alkalosis, according to the product package insert.

• Inspect the solution prior to use to ensure package integrity and the absence of visual alteration or precipitation.

Side Effects

Side effects or complications may occur, particularly with high doses or rapid administration, including:

• Hypernatremia (elevated blood sodium).

• Metabolic alkalosis.

• Fluid volume overload or fluid retention.

• Hypokalemia (low blood potassium).

• Electrolyte imbalance.

• Edema or pulmonary congestion in susceptible patients.

• Local irritation or tissue complications at the injection site in case of extravasation.

• The risk of certain complications increases in patients with heart failure or impaired renal function.

Storage Conditions

• Store at 20–25°C.

• Keep away from heat, direct light, and out of reach of children.

• Intended for single-dose use; once a portion is withdrawn, any remaining quantity must be discarded according to infection control procedures and institutional policy.

Ingredients

• Active Ingredient: Sodium Bicarbonate 8.4%. Each 1 ml contains 84 mg of sodium bicarbonate, equivalent to 1 mEq. The 50 ml vial contains a total of 50 mEq of sodium bicarbonate.

• Solvent: Water for Injection.