Sifrol 0.18Mg(0.25) 30Tab is a medication that contains the active ingredient Pramipexole. It is used to treat Parkinson’s disease and Restless Legs Syndrome (RLS). It belongs to a class of drugs known as dopamine agonists, as it works by stimulating dopamine receptors in the brain to improve motor control.
sifrol 0.18 uses
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Parkinson’s Disease:
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Helps relieve symptoms such as tremors, slowed movements, and muscle stiffness.
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Can be used alone or in combination with Levodopa at all stages of the disease.
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Restless Legs Syndrome (RLS):
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Treats moderate to severe symptoms when no clear underlying cause is identified, such as the persistent urge to move the legs.
How to Use Sifrol 30 Tablets
For Parkinson’s Disease
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The dosage is determined by the doctor.
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Initial dose: Usually 0.088 mg three times daily (for immediate-release tablets) or 0.26 mg once daily (for extended-release tablets).
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Dose may be gradually increased every 5–7 days.
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Maximum daily dose: 3.3 mg.
For Restless Legs Syndrome (RLS)
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The dosage is determined by the doctor.
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Immediate-release tablets are taken once daily, 2 to 3 hours before bedtime.
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Starting dose: 0.088 mg, which may be increased gradually every 4–7 days up to a maximum of 0.54 mg.
Administration Instructions
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Tablets should be swallowed with water.
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Extended-release tablets should not be chewed or crushed.
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Should be taken at approximately the same time each day.
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If the medication is stopped for a few days, treatment should be restarted at the lowest dose under medical supervision.
sifrol 0.18 side effects
Common side effects:
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In Parkinson’s: dyskinesia (involuntary movements), dizziness, drowsiness, nausea.
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In RLS: nausea.
Other possible side effects include:
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Hallucinations (seeing or hearing things that aren’t there).
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Sudden sleep attacks.
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Behavioral changes, such as compulsive overeating.
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Visual impairment.
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Low blood pressure when standing (orthostatic hypotension).
Precautions and Warnings
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Use with caution in cases of:
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Kidney disease.
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Cardiovascular conditions.
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Psychiatric disorders (e.g., psychosis or compulsive behaviors).
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Additional precautions:
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Regular monitoring of blood pressure and eye health is advised.
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Not recommended for children and adolescents under 18 years of age.
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May impair the ability to drive or operate machinery due to possible drowsiness or hallucinations.
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Consult your doctor before using this medication during pregnancy or breastfeeding.
Drug Interactions
Inform your doctor of all medications you are using. Use caution with:
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Antipsychotic medications.
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Cimetidine, Amantadine, Mexiletine, Zidovudine, Cisplatin, Quinine, and Procainamide.
Storage Instructions
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Store below 30°C.
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Keep in the original packaging to protect from light.
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Keep out of reach of children.
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Do not use after the expiry date stated on the package.
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Do not dispose of via wastewater or household waste—ask your pharmacist how to dispose of it properly.
Ingredients of Sifrol 30 Tablets
Active ingredient:
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Pramipexole.
Other ingredients:
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Mannitol.
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Maize starch.
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Colloidal anhydrous silica.
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Povidone K25.
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Magnesium stearate.
