Sifrol 0.18Mg(0.25) 30Tab is a medication that contains the active ingredient Pramipexole. It is used to treat Parkinson’s disease and Restless Legs Syndrome (RLS). It belongs to a class of drugs known as dopamine agonists, as it works by stimulating dopamine receptors in the brain to improve motor control.

sifrol 0.18 uses

• Parkinson’s Disease:

• Helps relieve symptoms such as tremors, slowed movements, and muscle stiffness.

• Can be used alone or in combination with Levodopa at all stages of the disease.

• Restless Legs Syndrome (RLS):

• Treats moderate to severe symptoms when no clear underlying cause is identified, such as the persistent urge to move the legs.

How to Use Sifrol 30 Tablets

For Parkinson’s Disease

• The dosage is determined by the doctor.

• Initial dose: Usually 0.088 mg three times daily (for immediate-release tablets) or 0.26 mg once daily (for extended-release tablets).

• Dose may be gradually increased every 5–7 days.

• Maximum daily dose: 3.3 mg.

For Restless Legs Syndrome (RLS)

• The dosage is determined by the doctor.

• Immediate-release tablets are taken once daily, 2 to 3 hours before bedtime.

• Starting dose: 0.088 mg, which may be increased gradually every 4–7 days up to a maximum of 0.54 mg.

Administration Instructions

• Tablets should be swallowed with water.

• Extended-release tablets should not be chewed or crushed.

• Should be taken at approximately the same time each day.

• If the medication is stopped for a few days, treatment should be restarted at the lowest dose under medical supervision.

sifrol 0.18 side effects

Common side effects:

• In Parkinson’s: dyskinesia (involuntary movements), dizziness, drowsiness, nausea.

• In RLS: nausea.

Other possible side effects include:

• Hallucinations (seeing or hearing things that aren’t there).

• Sudden sleep attacks.

• Behavioral changes, such as compulsive overeating.

• Visual impairment.

• Low blood pressure when standing (orthostatic hypotension).

Precautions and Warnings

• Use with caution in cases of:

• Kidney disease.

• Cardiovascular conditions.

• Psychiatric disorders (e.g., psychosis or compulsive behaviors).

• Additional precautions:

• Regular monitoring of blood pressure and eye health is advised.

• Not recommended for children and adolescents under 18 years of age.

• May impair the ability to drive or operate machinery due to possible drowsiness or hallucinations.

• Consult your doctor before using this medication during pregnancy or breastfeeding.

Drug Interactions

Inform your doctor of all medications you are using. Use caution with:

• Antipsychotic medications.

• Cimetidine, Amantadine, Mexiletine, Zidovudine, Cisplatin, Quinine, and Procainamide.

Storage Instructions

• Store below 30°C.

• Keep in the original packaging to protect from light.

• Keep out of reach of children.

• Do not use after the expiry date stated on the package.

• Do not dispose of via wastewater or household waste—ask your pharmacist how to dispose of it properly.

Ingredients of Sifrol 30 Tablets

Active ingredient:

• Pramipexole.

Other ingredients:

• Mannitol.

• Maize starch.

• Colloidal anhydrous silica.

• Povidone K25.

• Magnesium stearate.