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Sabril 500 mg tablets are used alongside other medications to treat refractory partial epilepsy, with or without secondary generalization.

Composition of Sabril

Each tablet contains 500 mg of vigabatrin, an antiepileptic agent that increases the concentration of GABA in the central nervous system, helping to inhibit nerve activity and thereby reduce seizures.

Sabril tablet uses

Used in combination with other antiepileptic drugs to treat partial seizures resistant to treatment, with or without secondary generalization.

Dosage of Sabril Tablets

  • The doctor determines the appropriate dosage based on the patient’s condition.
  • Usual dose: once or twice daily, before or after meals.
  • Tablets should be swallowed with half a glass of water.
  • The drug should be withdrawn gradually under medical supervision.
  • Maximum adult dose: 2–3 g per day.
  • Recommended starting dose for children: 40 mg/kg body weight, with maintenance dosage adjusted according to the child’s weight.

Sabril 500mg side effects

Sabril may cause some side effects, including:

  • Anemia.
  • Drowsiness.
  • Headache.
  • Dizziness.
  • Depression.
  • Irritability.
  • Visual field disturbances.
  • Joint pain.
  • Fever.
  • Weight gain.

Contraindications

Hypersensitivity to vigabatrin or any component of the drug.

Warnings and Precautions

Consult a physician before using Sabril during pregnancy or breastfeeding; it should only be used if clearly necessary.

Storage Instructions

  • Keep out of reach of children.
  • Store at a temperature not exceeding 30°C.
  • Do not use it after the expiry date.
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