Metoject 10Mg / 0.2Ml Methotrexate is an injection used to treat rheumatoid arthritis, as well as psoriasis and psoriatic arthritis, especially when other treatments have failed to control psoriasis.
Metoject Injection Ingredients
Metoject pre-filled syringes contain the active substance "Methotrexate," which inhibits several enzymes, helping to reduce inflammation and prevent cell division.
What are the uses of Metoject injections?
Metoject pen is used for the treatment of:
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Active rheumatoid arthritis in adults.
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Severe, treatment-resistant psoriasis that prevents the practice of normal daily life; this type of psoriasis does not respond to other forms of treatment, such as phototherapy and retinoids.
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Severe psoriatic arthritis in adults.
How to use Methotrexate (Metoject) injection?
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Methotrexate injections are administered subcutaneously (under the skin) once a week.
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The medication must be used according to the doctor's directions.
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The doctor determines the appropriate dose based on the patient's condition; it usually takes 4 - 8 weeks for the treatment effect to appear.
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Using this medication in large doses is fatal, so the dose prescribed by the doctor must be strictly followed.
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Metoject is not used for children younger than 3 years old.
Side Effects of Metoject
Methotrexate may cause some side effects, such as:
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Stomatitis (mouth inflammation).
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Indigestion.
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Loss of appetite.
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Abdominal pain.
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Abnormal liver function test results.
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Mouth ulcers.
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Diarrhea.
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Skin rash and itching.
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Skin redness.
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Headache, fatigue, and dizziness.
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Low blood cell count.
Contraindications
Do not use Metoject injections in cases of:
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Hypersensitivity to its components.
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Severe kidney or liver disease.
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Blood disorders.
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Regular consumption of large amounts of alcohol.
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Severe infections, such as tuberculosis, HIV, or any diseases causing immune deterioration.
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Mouth, stomach, or intestinal ulcers.
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Pregnancy and breastfeeding.
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Receiving live vaccines or immunizations concurrently with the medication.
Warnings and Precautions
A doctor must be consulted before using Methotrexate for rheumatoid arthritis, especially in cases of:
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Advanced age or feeling ill and weak.
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Liver problems.
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Dehydration.
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The medication should not come into contact with the skin surface or mucous membranes; if this occurs, the area must be washed with water immediately.
Metoject for Pregnant Women
Metoject injections are not recommended for pregnant women, as they may cause miscarriage or severe fetal deformities. Consequently, pregnancy must be avoided during treatment and for up to 6 months after stopping the medication.
Metoject and Breastfeeding
Breastfeeding must be discontinued before and during the use of Metoject injections for treatment.
Does Metoject affect fertility?
Metoject (Methotrexate) may have temporary effects on sperm production in men and egg production in women, but these effects are temporary.
Drug Interactions
A doctor or pharmacist must be consulted before using Metoject alongside any other medications, such as:
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Antibiotics.
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Non-steroidal anti-inflammatory drugs (NSAIDs), such as Ibuprofen.
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Probenecid.
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Diuretics.
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Other medications for rheumatoid arthritis, such as Sulfasalazine.
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Mercaptopurine.
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Retinoids (medications for psoriasis and skin diseases).
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Diabetes medications.
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Medications for stomach ulcers or GERD, such as Omeprazole.
Storage and Handling
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Keep out of reach of children.
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Store at a temperature below 25°C.
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Do not use the medication after its expiration date.
