Levonic Levofloxacin IV 750 mg 150 ml

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Levonic 750 mg/150 mL is an antibiotic solution for intravenous infusion containing the active ingredient levofloxacin, which belongs to a class of antibiotics known as fluoroquinolones. It works by inhibiting bacterial enzymes essential for DNA replication, helping eliminate bacteria susceptible to the active ingredient. It is used to treat specific types of bacterial infections, including certain cases of pneumonia and complicated urinary tract infections, as determined by medical diagnosis. It is supplied in a ready-to-use 150 mL intravenous infusion bag at a concentration of 5 mg/mL. It is available by prescription only and must be administered under the supervision of healthcare professionals.

Benefits and Features

  • Contains 750 mg of levofloxacin in a 150 mL infusion bag.

  • Provides a concentration of 5 mg/mL.

  • Used to treat bacterial infections caused by organisms susceptible to the active ingredient.

  • Available as an intravenous infusion solution, allowing administration when this route is required.

What is levofloxacin 750mg injection used for?

Levonic may be used to treat certain conditions when an infection caused by susceptible bacteria is confirmed or suspected, including:

  • Community-acquired pneumonia.

  • Certain cases of complicated urinary tract infections and kidney infections.

  • Certain skin and soft tissue infections.

  • Other specific infections as determined by medical evaluation.

How to Use Levonic 750 mg

  • It must be administered by intravenous infusion by a qualified healthcare professional.

  • The dose and duration of treatment are determined by the type and severity of the infection and the patient's kidney function.

  • The 750 mg dose is typically infused over 90 minutes.

  • It must not be administered as a rapid intravenous injection or direct IV bolus.

  • Other medications must not be added to the solution or administered through the same IV line without first confirming drug compatibility.

Precautions and Warnings

  • Use only with a prescription.

  • It is contraindicated in patients with a known allergy to levofloxacin or other quinolone antibiotics.

  • It may increase the risk of tendon inflammation or rupture, particularly in older adults and patients taking corticosteroids.

  • It may cause neurological side effects or heart rhythm disturbances in some patients.

  • The dose may need to be adjusted in patients with impaired kidney function.

  • Inform the doctor about pregnancy, breastfeeding, heart disease, heart rhythm disorders, or a history of seizures.

  • It should not be used to treat viral infections such as the common cold or influenza.

Side Effects

Possible side effects include:

  • Nausea, diarrhea, headache, and dizziness.

Less common but potentially serious side effects include:

  • Tendon inflammation or rupture, peripheral neuropathy, nervous system disorders, and QT interval prolongation on an electrocardiogram (ECG). New tendon pain or severe neurological symptoms require prompt medical evaluation.

Drug Interactions

Levofloxacin may interact with certain medications, including:

  • Drugs that prolong the QT interval, such as some antiarrhythmic medications.

  • Warfarin and other anticoagulants.

  • Medications that affect blood glucose levels.

  • Certain nonsteroidal anti-inflammatory drugs (NSAIDs), which may increase the risk of neurological effects in some patients.

All current medications should be reviewed before starting treatment.

Ingredients

  • Active ingredient: Levofloxacin 750 mg in 150 mL.

  • Concentration: 5 mg/mL.

  • Diluent: 5% dextrose solution, as used in commonly available ready-to-use intravenous levofloxacin formulations.

Storage and Handling

  • Store at room temperature, away from heat and moisture.

  • Keep out of reach of children.

  • Keep in the original packaging to protect from light.

  • Do not use if the packaging is damaged or the solution is not clear.