What is Isoniazid?

isoniazid 100mg tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB), an infectious disease that primarily affects the lungs. This medication belongs to a group of drugs specifically used to treat TB and should only be taken under medical supervision.

What is isoniazid 100mg used for?

Isoniazid contains the active ingredient isoniazid, an antibiotic that kills the bacteria responsible for tuberculosis by preventing them from building their protective cell wall.

How to use Isoniazid

• Take the medication exactly as prescribed by your doctor.

• Do not take this medication with food.

• Swallow the tablets whole with a glass of water.

• isoniazid dose per day:

• Adults: 4 to 5 mg per kg of body weight daily, not exceeding 300 mg/day.

• Special cases (e.g., tuberculous meningitis): Up to 10 mg/kg/day.

• Elderly: The doctor may reduce the dose due to decreased liver or kidney function.

• Isoniazid 100mg for children over 3 months: 10 to 15 mg/kg/day.

• Infants under 3 months: Use of isoniazid is not recommended.

isoniazid 100mg side effects

Isoniazid may cause some side effects, which do not occur in everyone. Serious symptoms that require immediate medical attention include:

• Liver problems: Yellowing of the skin or eyes, dark urine, fatigue, and nausea.

• Severe skin rash or peeling.

• Mental disturbances (e.g., hallucinations or delusions).

• Nerve problems such as tingling or numbness in hands or feet.

• Blood disorders or high blood sugar.

• Digestive, vision, or hearing issues.

Note: The risk of these side effects increases in people over 35 years of age, with high doses, or prolonged use.

Precautions and Warnings

Avoid taking this medicine if you:

• Are allergic to isoniazid or any of its ingredients.

• Have had liver problems caused by another medication.

Consult your doctor or pharmacist before using isoniazid if you:

• Have liver or kidney problems.

• Consume large amounts of alcohol (it is best to avoid alcohol during treatment).

• Have diabetes, extrapulmonary TB, or HIV.

• Suffer from mental illness, malnutrition, epilepsy, or seizures.

• Take medications such as itraconazole (antifungal), which is not recommended with isoniazid.

Drug Interactions

Inform your doctor about all medications you are taking, including herbs and supplements, as isoniazid may interact with many drugs, such as:

• Other TB drugs (e.g., rifampicin, cycloserine).

• Epilepsy drugs (e.g., carbamazepine, phenytoin).

• HIV medications (e.g., stavudine).

• Medicines for anxiety, asthma, blood pressure, Parkinson’s disease, and fungal infections (e.g., ketoconazole).

• Vitamin B6 and B3 supplements.

Storage Instructions

• Keep out of reach of children.

• No special storage conditions are required.

• Do not use the medication after the expiry date printed on the package.

Ingredients

• Active ingredient: Each tablet contains 100 mg of isoniazid.

• Other ingredients:

• Calcium hydrogen phosphate.

• Dried corn starch.

• Talcum powder.

• Colloidal anhydrous silica.

• Magnesium stearate.