Invega Sustenna 75 mg injection is used for treating schizophrenia. It is administered after oral antipsychotic treatment to continue the therapeutic journey and relieve associated symptoms.

Invega Sustenna injection ingredients

Each Invega Sustenna injection contains 75 mg of paliperidone palmitate, an antipsychotic agent that helps alleviate schizophrenia symptoms by acting on dopamine and serotonin receptors.

Invega Sustenna monthly injection uses

Invega Sustenna injections are used to treat schizophrenia in adults who have been previously stabilized on oral paliperidone or risperidone.

Invega Sustenna administration guidelines

• Invega Sustenna is for intramuscular injection only.

• It should be administered by a healthcare professional.

• The initial dose is 150 mg on day one.

• The dose is reduced to 100 mg on day eight.

• Both initial doses are administered in the deltoid muscle.

• The third injection is given one month after the second dose. A maintenance dose of 75 mg monthly is recommended (dose may vary depending on the patient’s condition), and can be administered in the deltoid or gluteal muscle.

Invega Sustenna dosage schedule

Dosage varies based on the previous medication and dosage used by the patient. If the patient was previously on extended-release oral paliperidone, the dosing may be as follows:

If the patient was previously on long-acting risperidone injections:

Invega Sustenna side effects

Possible side effects may include:

• Injection site reactions (pain, redness, or swelling)

• Drowsiness

• Dizziness

• Weight changes

• Increased blood pressure

• Increased heart rate

• Amenorrhea in women

• Gastrointestinal disturbances

Contraindications

Do not use Invega Sustenna in patients with known hypersensitivity to its ingredients.

Warnings and Precautions

Consult a doctor before using Invega Sustenna, especially in cases of:

• History of Neuroleptic Malignant Syndrome (a serious reaction to antipsychotics causing sudden fever, increased heart rate, severe blood pressure changes, etc.)

• Tardive dyskinesia (involuntary movements of the face, tongue, limbs)

• Dehydration

• Excessive sweating

• Diarrhea

• Seizures

• Dizziness when standing

• Hypertension or hypotension

• Irregular heartbeats

• Kidney or liver problems

• Parkinson’s disease

• Diabetes

• Low white blood cell count

• Eye surgery planning

• Pregnancy or breastfeeding

Drug Interactions

Always consult a doctor or pharmacist before combining Invega Sustenna with other medications, especially:

• Sedatives

• Sleep aids

• Antiepileptics

• Psychiatric medications

• Antihypertensives

• Antiemetics

• Antimalarials

Storage Instructions

• Keep out of reach of children.

• Store below 25°C in a cool, dry place.