Deprix Antidepressant Tablets 1mg 30 Tablets

What is debrex?

Debrex 1 mg (30 tablets) is a prescription medication containing the active ingredient Brexpiprazole at a concentration of 1 mg. Belonging to the class of atypical antipsychotics, it is used in adults to treat schizophrenia and as an adjunctive (add-on) treatment to antidepressants for major depressive disorder when antidepressant therapy alone is insufficient.

What is Debrex used to treat?

• As an adjunctive treatment for major depressive disorder in adults, based on medical evaluation.

• To treat symptoms of schizophrenia in adults.

How to Use Debrex 1 mg

• Take one tablet once daily, with the exact dosage determined by your doctor based on your condition.

• It can be taken with or without food.

• Do not alter the dose or stop taking the medication without consulting your doctor.

• Treatment usually starts at a low dose and is gradually increased based on response and tolerability.

• In cases of moderate to severe hepatic or renal impairment, or when co-administering drugs that affect liver enzymes, your doctor may adjust the dose.

Precautions and Warnings

• This medication must be used under medical supervision and is available by prescription only.

• It may cause drowsiness or dizziness; exercise caution when driving or operating machinery until you know how the medication affects you.

• Inform your doctor prior to use if you have: cardiovascular disease, low blood pressure, a history of seizures, or a low white blood cell count.

• Treatment may lead to weight gain, elevated blood sugar, or changes in lipid levels; your doctor may monitor your weight and health parameters during therapy.

• Contact your doctor immediately if you experience involuntary movements, severe muscle stiffness, high fever, confusion, or unusual symptoms.

• Certain medications may increase or decrease blood levels of Brexpiprazole, requiring a dose adjustment.

• Patients should be monitored for the emergence or worsening of suicidal thoughts, particularly at the start of treatment or following dose adjustments.

• Consult your doctor before use if you are pregnant or breastfeeding.

Side Effects of Debrex 1mg 30 Tablets

Common side effects may include:

• Weight gain

• Restlessness or inability to sit still (akathisia)

• Drowsiness or fatigue

• Dizziness

• Impaired thinking or difficulty performing routine activities

• Cold-like symptoms

• Headache, tremors, or anxiety

Less common but serious side effects may occur, such as low blood pressure, seizures, movement disorders, high blood sugar, or Neuroleptic Malignant Syndrome (NMS). If severe or unusual symptoms appear, contact your doctor immediately.

Drug Interactions

Brexpiprazole may interact with medications that affect CYP2D6 and CYP3A4 enzymes, potentially altering drug concentrations in the blood. Examples include:

• Strong CYP2D6 or CYP3A4 inhibitors (e.g., clarithromycin, diltiazem, itraconazole, ketoconazole, paroxetine, fluoxetine).

• Strong CYP3A4 inducers (e.g., rifampicin, phenytoin, phenobarbital, St. John's Wort).

Dose adjustments may be necessary when combining these agents. Inform your doctor or pharmacist of all medications and supplements you take before starting treatment, and do not begin new medications without professional advice.

Storage Instructions

• Store Deprex at room temperature, ideally between 20°C and 25°C, with excursions permitted between 15°C and 30°C.

• Keep out of reach of children.

• Store in the original package, away from heat and moisture.

Ingredients of Debrex 1mg 30 Tablets

• Active Ingredient: Brexpiprazole 1 mg per tablet.