Cinac Cinacalcet Calcium Regulation Tablets 30mg 28 Tablets

What is Cinac?

Cinac 30 mg (28 tablets) is a prescription medication containing Cinacalcet Hydrochloride. It works by increasing the sensitivity of calcium-sensing receptors on the parathyroid glands, which helps lower parathyroid hormone (PTH) levels and regulate calcium and phosphorus levels in the blood. It is primarily used to treat secondary hyperparathyroidism in patients with chronic kidney disease (CKD) on dialysis. It may also be used in specific cases of primary hyperparathyroidism and parathyroid carcinoma based on a doctor's evaluation.

Uses of Cinac 30 mg

• Helps lower parathyroid hormone (PTH) levels.

• Contributes to regulating calcium and phosphorus levels in the blood.

• Used to treat secondary hyperparathyroidism in certain patients with chronic kidney disease undergoing dialysis.

• May be used in specific cases of primary hyperparathyroidism and parathyroid carcinoma as prescribed by a physician.

How to Use Cinac Cinacalcet 30 mg

• Use strictly as prescribed by your doctor. Do not adjust the dose or stop treatment without consulting your physician.

• Swallow tablets whole with water; do not chew, crush, or divide them.

• Can be taken with food or shortly after a meal, preferably at the same time each day.

• Dosage varies based on the condition, serum calcium, and PTH levels. For secondary hyperparathyroidism, the starting dose is typically 30 mg once daily, which the doctor may adjust gradually based on lab results and response. Other conditions may require different dosing schedules.

Precautions and Warnings

• Available by prescription only and must be used under medical supervision.

• Blood calcium levels must be measured regularly during treatment.

• Do not initiate treatment if baseline blood calcium levels are low (hypocalcemia).

• Inform your doctor prior to use if you have a history of seizures, liver disease, or heart conditions.

• Pay close attention to symptoms of low calcium (hypocalcemia), such as numbness or tingling around the mouth, muscle cramps, spasms, or seizures.

• May cause dizziness; exercise caution when driving or operating machinery.

• Inform your doctor of all medications and supplements you take prior to starting treatment.

Side Effects

Possible side effects may include:

• Nausea and vomiting

• Diarrhea or constipation

• Headache

• Dizziness

• Low blood pressure (hypotension)

• General weakness or fatigue

• Decreased appetite

• Muscle pain

• Low blood calcium levels (hypocalcemia)

More serious complications can occur if calcium levels drop significantly, leading to severe muscle cramps, tingling/numbness, or seizures. Seek immediate medical attention if you experience swelling of the face, lips, or tongue, or difficulty breathing or swallowing.

Drug Interactions

Cinacalcet may interact with several medications. Inform your doctor or pharmacist of all drugs you take, particularly:

• Medications that affect calcium levels.

• Medications used for high blood pressure or cardiac disorders.

• Medications that influence liver enzymes responsible for drug metabolism.

• Certain drugs used to treat epilepsy or infections.

• Etelcalcetide: Concomitant use with cinacalcet is contraindicated.

Dose adjustments for Cinac or co-administered drugs may be necessary when used together.

Storage Instructions

• Keep out of reach of children.

• Does not require special storage conditions.

• Preferably store in the original packaging and do not use past the expiration date stated on the carton.

Ingredients

• Active Ingredient: Cinacalcet Hydrochloride (equivalent to 30 mg of Cinacalcet per tablet).

• Inactive Ingredients (Excipients): Lactose monohydrate (or hydrous lactose), microcrystalline cellulose, pregelatinized starch, crospovidone, magnesium stearate, talc.

• Film Coating: Hypromellose (hydroxypropyl methylcellulose), titanium dioxide, lactose monohydrate, triacetin, yellow iron oxide, indigotine aluminum lake.