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Pentasa 1 g Rectal Enema, used for the treatment of ulcerative colitis, specifically ulcerative proctosigmoiditis; it helps relieve inflammation.

Composition of Pentasa Enema

Pentasa rectal enema contains the active ingredient Mesalazine, an anti-inflammatory for the intestines, used in the treatment of ulcerative colitis and Crohn’s disease.

Pentasa enema uses

Pentasa rectal enema is used in the treatment of ulcerative colitis, specifically ulcerative proctosigmoiditis.

Pentasa enema dose

  • The usual dose is one rectal enema before bedtime.

Pentasa enema 1g how to use

  • It is recommended to empty the bowels before using Pentasa.

  • Lie on your left side, keeping the left leg straight and bending the right leg forward for balance.

  • Gently insert the applicator tip into the rectum, maintaining steady and sufficient hand pressure while dispersing the bottle content.

  • The entire bottle content should be administered within 30–40 seconds.

  • Once the bottle is empty, withdraw the applicator tip while keeping the bottle compressed.

  • The rectal suspension should be retained in the colon. Stay relaxed in the administration position for 5–10 minutes, or until the urge to pass the rectal suspension has disappeared. It is recommended to try to retain the enema overnight.

Pentasa enema side effects

Pentasa rectal enema may cause some side effects, such as:

  • Diarrhea

  • Nausea

  • Abdominal pain

  • Headache

  • Vomiting

  • Skin rash

Contraindications

Pentasa rectal enema should not be used in cases of:

  • Hypersensitivity to its components

  • Kidney or liver impairment

Warnings and Precautions

Caution and medical advice are required before using Pentasa enema, especially in patients with:

  • Hypersensitivity to sulfasalazine

  • Respiratory diseases such as asthma

  • Kidney stones

  • Pregnancy or breastfeeding

Storage Instructions

  • Keep out of the reach of children.

  • Store at a temperature not exceeding 30 °C.

  • Do not freeze or refrigerate.

  • Keep in the original package, protected from light.

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