One-Alpha 0.25 mcg is a medicine that contains the active ingredient Alfacalcidol, a form of vitamin D that is converted inside the body into the active form of vitamin D. It helps the body regulate calcium and phosphate levels, which are essential for healthy bones and teeth.
One-Alpha works differently from regular vitamin D, so it is used in specific cases determined by the doctor, especially when the body is unable to activate vitamin D properly.
What is One-Alpha 0.25 mcg used for?
One-Alpha 0.25 mcg is used to help treat certain conditions related to active vitamin D deficiency or calcium imbalance in the body. Its main uses include:
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Supporting bone health in some kidney patients who have bone problems due to impaired kidney function.
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Treating certain cases of hypoparathyroidism, whether present from birth or occurring after surgery.
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It may be used as an additional treatment in some cases of hyperparathyroidism, according to the doctor’s assessment.
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Helping treat certain types of rickets or osteomalacia, especially cases that do not respond well to regular vitamin D.
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Helping with osteomalacia or rickets caused by poor nutrition or reduced absorption of nutrients.
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It may be used in some cases of postmenopausal osteoporosis, as prescribed by the doctor.
Directions for Use
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The dose of One-Alpha is determined according to the patient’s health condition, age, test results, and calcium and phosphate levels in the blood. Therefore, it should not be used or the dose changed without consulting a doctor.
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The doctor usually determines the appropriate dose, then may adjust it later based on test results to avoid high calcium levels in the blood.
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In some cases, the patient may need to take calcium supplements alongside the medicine, especially if dietary calcium intake is not enough. However, this should only be done under medical guidance.
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Follow the dose prescribed by your doctor, and do not double the dose or stop the medicine on your own.
Side Effects
One-Alpha may cause side effects in some people. Possible side effects include:
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High calcium levels in the blood.
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High phosphate levels in the blood.
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Increased calcium in the urine.
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Abdominal pain or discomfort.
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Nausea or digestive discomfort.
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Skin rash, redness, or blisters.
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Itching.
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Muscle pain.
Consult your doctor if you notice any unusual symptoms or if side effects persist for a long time.
Precautions and Warnings
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One-Alpha should not be used if you have high calcium levels in the blood or if you are allergic to the active ingredient or any component of the medicine.
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This medicine requires regular medical follow-up. Your doctor may request periodic tests to monitor calcium and phosphate levels, as well as body functions related to bones and the parathyroid glands.
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Tell your doctor immediately if you notice symptoms that may indicate high calcium levels, such as:
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Loss of appetite.
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Nausea or vomiting.
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Headache.
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Severe thirst.
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Constipation or diarrhea.
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Unusual weakness or tiredness.
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Frequent urination.
If these symptoms occur, your doctor may ask you to stop the medicine temporarily or adjust the dose.
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One-Alpha is not recommended during pregnancy unless necessary and under close medical supervision. You should also consult your doctor before using it while breastfeeding.
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The capsules contain sesame oil, which may cause allergic reactions in some people. Tell your doctor if you are allergic to sesame or similar oils.
Drug Interactions
Tell your doctor or pharmacist about all medicines and supplements you use before taking One-Alpha, especially:
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Thiazide diuretics may increase the risk of high calcium levels in the blood.
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Calcium or vitamin D supplements may raise calcium levels if used without monitoring.
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Some epilepsy medicines, such as phenytoin and barbiturates, may reduce the effect of the medicine.
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Magnesium-containing antacids, as they may increase magnesium levels in the blood.
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Aluminum-containing medicines may increase the risk of aluminum accumulation in the body.
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Cholestyramine, as it may reduce the absorption of One-Alpha. The patient may need to separate the timing of doses according to the doctor’s instructions.
Storage
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Store One-Alpha in a dry place, away from moisture and heat.
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Store at a temperature not exceeding 25°C.
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Keep out of reach of children.
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Do not use the medicine after the expiry date printed on the package.
Ingredients
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Active ingredient: Alfacalcidol 0.25 mcg per capsule.
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Inactive ingredients: Sesame oil, DL-alpha-tocopherol, gelatin, glycerol, potassium sorbate, and titanium dioxide.
