LINZESS 290 MCG 30 CAPS

Linzess 290 mcg is a medication containing the active ingredient linaclotide. It is used to treat irritable bowel syndrome with constipation (IBS-C) in adults. The drug acts locally in the intestines by activating guanylate cyclase-C receptors, which increases fluid secretion into the intestinal lumen and accelerates intestinal transit. This helps soften stools, facilitate bowel movements, and relieve abdominal pain and discomfort associated with IBS.

Linzess 290 mcg capsule uses

• Treatment of Irritable Bowel Syndrome with Constipation (IBS-C): Indicated for adults.

• Treatment of Chronic Idiopathic Constipation (CIC): Indicated for adults at appropriate dosages determined by a physician.

• Improves Stool Parameters: Increases bowel movement frequency and improves stool consistency.

• Symptom Relief: Helps reduce abdominal pain and bloating associated with IBS-C.

• Promotes Regularity: Facilitates bowel movement and reduces the sensation of constipation.

How to Use Linzess 290 mcg

• Standard Dosage: The usual adult dose for IBS-C is 290 mcg once daily.

• Timing: Best taken on an empty stomach, approximately 30 minutes before the first meal of the day, at the same time every day.

• Administration: Swallow the capsule whole with a sufficient amount of water. Do not crush or chew.

• Alternative Administration: If swallowing is difficult, the capsule may be opened and the contents sprinkled onto a small amount of applesauce or mixed with water to be consumed immediately (do not store the mixture). It can also be administered via a nasogastric or gastric feeding tube under medical direction.

• Missed Dose: Skip the missed dose and resume the regular schedule. Do not take a double dose to make up for a missed one.

Linzess 290 mcg capsule side effects

Linzess may cause side effects, including:

• Diarrhea (most common)

• Abdominal pain or cramping

• Abdominal distension / bloating

• Flatulence (gas)

• Nausea, and occasionally vomiting

Important: In rare cases, severe diarrhea leading to dehydration may occur. If this happens, discontinue the medication and contact a doctor immediately.

Precautions and Warnings

• Contraindications: Do not use in patients with known or suspected mechanical gastrointestinal obstruction.

• Pediatric Warning: Contraindicated in children under 2 years of age due to the risk of severe dehydration.

• Dehydration Signs: Notify a doctor immediately if severe diarrhea occurs or signs of dehydration appear (e.g., dizziness, lightheadedness, or decreased urination).

• Medical Supervision: Use strictly as directed by your healthcare provider.

Storage and Handling

• Store at controlled room temperature between 20°C and 25°C (68°F to 77°F), with excursions permitted between 15°C and 30°C (59°F to 86°F).

• Keep inside the original bottle along with the desiccant pack to protect from moisture.

• Keep away from excessive heat, moisture, and out of reach of children.

Ingredients

Active Ingredient

• Linaclotide: 290 mcg per capsule.

Inactive Ingredients (Excipients)

• Calcium chloride, L-leucine, hypromellose, and capsule shell components.