Carelio 50 Mg Retard 30 Tab

Carelio Tablets is used to treat: 

1. Diabetic nephropathy
2. Hypertension

Doses

1. Adult Dose

- Hypertension

Adult: 150 mg once daily, may increase to 300 mg once daily if needed. Patient w/ intravascular volume depletion: Initially, 75 mg once daily.

Elderly: >75 yr Initially, 75 mg once daily. 

- Diabetic nephropathy in Type 2 diabetes mellitus

Adult: Initially, 75-150 mg once daily, may increase to 300 mg once daily if needed.

Child Dose

Hypertension

<6 years: Safety and efficacy not established

6-12 years: 75 mg/day PO initially; not to exceed 150 mg/day

>12 years: 150 mg/day PO initially; may be increased to 300 mg/day PO

Renal Dose

Renal impairment: 

Haemodialysis: Initially, 75 mg once daily. 

Mild-to-severe renal impairment: Dosage adjustment not necessary unless patient is hypovolemic

May be taken with or without food.

Pregnancy-Lactation

C) possible side effects

1. Hyperkalemia (19%)
2. Dizziness (10%)
3. Upper respiratory tract infection (URTI) (9%)
4. Orthostatic hypotension (5%)
5. Fatigue (4%)
6. Diarrhea (3%)
7. Dyspepsia (2%)