Product Description:

 

Venlafaxine is an antidepressant belonging to a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs).

Venlafaxine affects chemicals in the brain that may be unbalanced in people with depression.

Venlafaxine is a prescription medicine used to treat major depressive disorder, anxiety, and panic disorder.

Dosage forms:

 

Oral capsule, extended release (150 mg; 37.5 mg; 75 mg).

Oral tablet (100 mg; 25 mg; 37.5 mg; 50 mg; 75 mg).

oral tablet, extended release (150 mg; 225 mg; 37.5 mg; 75 mg).

How To Use:

 

Usual Adult Dose for Depression:

 

Immediate release:

 

Initial dose:

 

5 mg orally twice a day OR 25 mg orally 3 times a day.

Maintenance dose:

 

75 to 150 mg orally per day, given in divided doses.

Maximum dose:

 

Moderately depressed outpatients: 225 mg/day.

Severely depressed inpatients: 375 mg/day.

Extended release:

 

Initial dose:

 

75 mg orally once a day.

Maintenance dose:

 

75 to 225 mg orally once a day.

Maximum dose:

 

Moderately depressed outpatients: 225 mg/day.

Severely depressed inpatients: 375 mg/day.

Comments:

 

 

 

The daily dosage of immediaterelease formulations may be divided into 2 or 3 doses/day.

Healthcare providers should consider initial extended release doses of 37.5 mg orally once a day for 4 to 7 days (before increasing the dose to 75 mg/day) in patients who may require additional time to adjust to the drug.

Doses may be increased in daily increments of up to 75 mg orally at intervals of no less than 4 days.

Patients should be periodically reassessed for the continued need of maintenance treatment and for the appropriate dose of treatment.

Use of doses exceeding 225 mg/day is limited.

 

Use:

 

Treatment of major depressive disorder (MDD)

 

Usual Adult Dose for Generalized Anxiety Disorder:

 

Extended release:

 

Initial dose:

 

75 mg orally once a day.

Maintenance dose:

 

75 to 225 mg orally once a day.

Maximum dose:

 

225 mg/day.

Comments:

 

Healthcare providers should consider initial extended release doses of 37.5 mg orally once a day for 4 to 7 days (before increasing the dose to 75 mg/day) in patients who may require additional time to adjust to the drug.

Doses may be increased in daily increments of up to 75 mg orally at intervals of no less than 4 days.

Use:

 

Treatment of generalized anxiety disorder (GAD)

 

Usual Adult Dose for Social Anxiety Disorder:

 

Extended release:

 

75 mg orally once a day.

Comment:

 

There is no evidence that doses greater than 75 mg/day confer additional benefit.

Uses:

 

Treatment of social anxiety disorder (SAD)

 

Treatment of social phobia:

 

Usual Adult Dose for Panic Disorder:

 

Extended release:

 

Initial dose:

 

5 mg orally once a day for 7 days, then 75 mg orally once a day thereafter.

Maintenance dose:

 

75 to 225 mg orally once a day.

Maximum dose:

 

225 mg/day.

Comment:

 

Doses may be increased in daily increments of 75 mg orally at intervals of no less than 7 days.

Warnings And precautions:

 

You should not take venlafaxine if you have uncontrolled narrowangle glaucoma.

Do not use venlafaxine within 7 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.

Some young people have thoughts about suicide when first taking an antidepressant.

Stay alert to changes in your mood or symptoms.

Report any new or worsening symptoms to your doctor, such as:

 

Mood or behavioral changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Do not stop using venlafaxine without first talking to your doctor.

Do not give this medicine to anyone younger than 18 years old without the advice of a doctor. Venlafaxine is not FDA approved for use in children.

Ingredients:

 

VENLAFAXINE