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. Active Ingredient: Dinoprostone (a synthetic prostaglandin E2)


2. Dosage Form: Vaginal gel


3. Mechanism of Action:


Ripens the cervix (softening and thinning) by stimulating contraction of cervical smooth muscle fibers.

Increases uterine prostaglandin production, further stimulating contractions.

May also increase fetal lung maturity.

4. Therapeutic Indications:


Induction of labor at term (38-42 weeks gestation):

When labor has not started spontaneously.

When there are medical reasons to induce labor, such as maternal or fetal health concerns.

Cervical ripening before other obstetric procedures:

Vacuum-assisted vaginal delivery.

Caesarean section.

5. Method of Administration:


Single application of 1mg gel inserted high into the posterior vaginal vault using a disposable applicator.

Repeat application up to four times at 6-hourly intervals if necessary.

Continuous fetal and maternal monitoring throughout treatment.

6. Non-Pharmacological Treatments & Advice:


Discuss alternative methods of labor induction with your doctor: Membrane sweeping, Foley catheter placement, amniotomy.

Prepare for labor naturally: Stay active, practice relaxation techniques, eat a healthy diet, get adequate sleep.

Manage potential side effects: Fever, chills, nausea, vomiting, diarrhea, uterine hyperstimulation (excessive contractions).

 

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